You must defeat the enemy with your hero's basic attack, which is very restrictive.
Hulk can +10 with a basic attack via event and Drax can reach the same amount (yet they are both of the worst characters of all the game).
3 Base ATK heroes can somewhat try to benefit from it, as long as the deck is built around buffing basic ATKs and/or making various basic ATKs per turn.
On the brighter side, this card is permanent and will stay for future reusagement (at the cost of your life)