Gambit - Med Lab Leadership

Rogue is the most powerful card Gambit has. The goal is to Med Lab Rogue infinitely. Utopia is 100% used to ready the exhausted Med Lab character. Gambit should flip every turn, so a lot of his cards need to function under this premise. You don't need to chump block too much. Crew Quarters and X-Mansion do a rather good job of keeping Gambit healthy, since you are only being attacked once every two turns.

You want to prioritize Med Lab in this list, Rogue can be fished out with Mutant Education or Pixie eventually. Sometimes Rogue is at the bottom of your deck. Weapon X has been great when Rogue is inevitably hiding at the bottom of the deck.

Lets talk about Mutant Education. It helps Gambit recycle Molecular Acceleration early game. Later on you'll probably want to finish the game with recycled Charged cards. Honorable mention using Creole Charmer when applicable (some villains are immune or less concerned). Obviously, keeping Rogue around is nice whenever possible. A cantrip is extremely powerful in all card games. You can decide to return nothing, thus thinning your deck. This is optimal when searching for specific cards. For example, early game you are looking for the danger room engine + Med lab. Then you need Rogue. Champions isn't a 1 for 1 comparison to other card games though. For example, getting a double resource is somewhat equal to drawing two cards. More molecular accelerations early game means you are setting up for end game more quickly/efficiently. I can see people arguing that X-mansion is too much of a tax for Gambit. Those people are not entirely wrong, but Weapon X is too good to pass up. Gambit's identity cards are great, and sometimes drawing a card is just a free resource to pay for something else.

Mirage + Danger Room Training = Often can stun villains Pixie + Danger room Training = She can attack and fall into the med lab next turn (or block)

Gambit works rather well with other X-men, since he's not too greedy with cards. X-mansion isn't that popular outside of Gambit. You can opt to share Danger Room. Let the other X-men player put Utopia in play (they might need the +1 ally limit). Moira MacTaggert is designed for sharing, which is phenomenal.

Lastly, it seems Med Lab works on your teammate's allies? This is certainly interesting! Maybe recur those busted Red Skull campaign allies! Perhaps share your friend's forge, Prof X, etc.